Biodegradable Polymeric Microparticles in Biomedical Applications
作者： K. Z. Gumargalieva , Daniel Horak , G. E. Zaikov
DOI: 10.1080/00914039808041062
关键词: Molar mass distribution 、 Materials science 、 Drug carrier 、 Biodegradation 、 Polymer 、 Particle size 、 Nanotechnology 、 Nanoparticle 、 Drug 、 Solubility
摘要: Abstract Factors affecting the drug release from biodegradable microparticles are reviewed. It is shown that spherical ranging in diameters below 1μ to over 100μ along with nanoparticles size less than 1000nm particularly effective. The role of molecular weight, weight distribution and co-polymer ratio also discussed. Important parameters solubility biological fluids possible polymer particle-drug interactions. microporosity may be essential delivery high substances.
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