Effect of Basic Factors of Preparation on Characteristics, Hydrolytic Degradation, and Drug Release From Poly(ester-anhydride) Microspheres
作者： Katarzyna Jaszcz
DOI: 10.1080/00914037.2013.769254
关键词: Morphology (linguistics) 、 Emulsion 、 Chemical engineering 、 Materials science 、 Condensation polymer 、 Polymer 、 Phase inversion 、 Aqueous two-phase system 、 Polyvinyl alcohol 、 Polymer chemistry 、 Sebacic acid
摘要: Functional poly(ester-anhydride) microspheres were prepared using emulsion solvent evaporation (ESE) and phase inversion methods (PIM). The poly(ester-anhydride)s obtained by polycondensation of sebacic acid (SBA) oligo(3-allyloxy-1,2-propylene succinate) terminated with carboxyl groups (OSAGE). effects various parameters, including: polymer emulsifier concentrations, stirring speed molecular weight polyvinyl alcohol (PVA) used as on size, size distribution morphology ESE technique examined. was in the range 2–30 µm depended mainly rate formulation process, well concentration solution used. Molecular PVA, its aqueous phase, significantly influenced tendency to agglomeration microparticles formed, but only slightly changed microspheres. present study demonstrated that method can be useful fo...
sci-hub.se 参考文章(41)
Zhihua Zhou, Lihua Liu, Qingquan Liu, Yanmin Zhao, Guorong Xu, Anping Tang, Wennan Zeng, Qingfeng Yi, Jianan Zhou, Study on Controlled Release of 5-Fluorouracil from Gelatin/Chitosan Microspheres Journal of Macromolecular Science, Part A. ,vol. 49, pp. 1030- 1034 ,(2012) , 10.1080/10601325.2012.728464
Lizhi Xiong, Zeqiang He, Release Behavior and Cytotoxicity of Poly(vinyl alcohol)/Chitosan Blend Microspheres Containing 2,4-Dihydroxy-5-Fluoropyrimidine Polymer-plastics Technology and Engineering. ,vol. 51, pp. 729- 733 ,(2012) , 10.1080/03602559.2012.663035
Allan S. Hoffman, The origins and evolution of “controlled” drug delivery systems Journal of Controlled Release. ,vol. 132, pp. 153- 163 ,(2008) , 10.1016/J.JCONREL.2008.08.012
Rocio Herrero-Vanrell, Miguel F Refojo, Biodegradable microspheres for vitreoretinal drug delivery Advanced Drug Delivery Reviews. ,vol. 52, pp. 5- 16 ,(2001) , 10.1016/S0169-409X(01)00200-9
Katarzyna Jaszcz, Jan Łukaszczyk, Monika Śmiga-Matuszowicz, Synthesis of functional poly(ester-andydride)s based on succinic acid Reactive & Functional Polymers. ,vol. 68, pp. 351- 360 ,(2008) , 10.1016/J.REACTFUNCTPOLYM.2007.07.051
Katarzyna Jaszcz, Jan Łukaszczyk, Studies on hydrolytic degradation of poly(ester-anhydride)s based on oligosuccinate and aliphatic diacids Polymer Degradation and Stability. ,vol. 96, pp. 1973- 1983 ,(2011) , 10.1016/J.POLYMDEGRADSTAB.2011.08.007
Jie Li, Shujun Wang, Hongyan Liu, Long You, Preparation of Polycarbonate Hollow Microspheres by Microencapsulation Method International Journal of Polymeric Materials. ,vol. 60, pp. 1041- 1055 ,(2011) , 10.1080/00914037.2010.551358
Jan Łukaszczyk, Monika Śmiga-Matuszowicz, Katarzyna Jaszcz, Teerapol Srichana, Preliminary Studies on the Hydrolytic Degradation and Biocompatibility of Poly(3-allyloxy-1,2-propylene succinate) Journal of Biomaterials Science-polymer Edition. ,vol. 21, pp. 691- 700 ,(2010) , 10.1163/156856209X435826
A. Peter Morello, Natalie Forbes, Edith Mathiowitz, Investigating the effects of surfactants on the size and hydrolytic stability of poly(adipic anhydride) particles. Journal of Microencapsulation. ,vol. 24, pp. 40- 56 ,(2007) , 10.1080/02652040601058467
Diba Behnoodfar, Susan Dadbin, Masoud Frounchi, PLA Microspheres-Embedded PVA Hydrogels Prepared by Gamma-Irradiation and Freeze-Thaw Methods as Drug Release Carriers International Journal of Polymeric Materials. ,vol. 62, pp. 28- 33 ,(2013) , 10.1080/00914037.2011.641648