A randomized clinical trial of two different durations of oral cryotherapy for prevention of 5‐fluorouracil‐related stomatitis

作者: Luann K. Rocke , Charles L. Loprinzi , Jeraldine K. Lee , Susan J. Kunselman , Rita K. Iverson

DOI: 10.1002/1097-0142(19931001)72:7<2234::AID-CNCR2820720728>3.0.CO;2-N

关键词: RandomizationBolus (medicine)Randomized controlled trialSurgeryCryotherapyMedicineClinical trialStomatitisChemotherapy regimenMucositis

摘要: … demonstrated that 30 minutes of oral cryotherapy, given at … oral mucositis.* The underlying hypothesis behind this initial trial was that oral cryotherapy would reduce blood flow to the oral …

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