Biochemical modulation of fluorouracil: evidence of significant improvement of survival and quality of life in patients with advanced colorectal carcinoma.
作者： M A Poon , M J O'Connell , C G Moertel , H S Wieand , S A Cullinan
DOI: 10.1200/JCO.1989.7.10.1407
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摘要: … this study was to evaluate … was 7.7 months. The high- and low-dose leucovorin plus 5-FU regimens had median survivals of 12.2 and 12.0 months, respectively, and offered a significant …
sci-hub.se 参考文章(21)
PJ Loehrer Sr, LH Einhorn, SD Williams, SL Hui, NC Estes, K Pennington, None, Cisplatin plus 5-FU for the treatment of adenocarcinoma of the colon. Cancer treatment reports. ,vol. 69, pp. 1359- 1363 ,(1985)
C J Allegra, R L Fine, J C Drake, B A Chabner, The effect of methotrexate on intracellular folate pools in human MCF-7 breast cancer cells. Evidence for direct inhibition of purine synthesis. Journal of Biological Chemistry. ,vol. 261, pp. 6478- 6485 ,(1986) , 10.1016/S0021-9258(19)84587-8
Ed Cadman, Chris Benz, Modulation of 5-Fluorouracil Metabolism and Cytotoxicity by Antimetabolite Pretreatment in Human Colorectal Adenocarcinoma HCT-8 Cancer Research. ,vol. 41, pp. 994- 999 ,(1981)
E. Cadman, R. Heimer, C. Benz, The influence of methotrexate pretreatment on 5-fluorouracil metabolism in L1210 cells Journal of Biological Chemistry. ,vol. 256, pp. 1695- 1704 ,(1981) , 10.1016/S0021-9258(19)69863-7
Khandan K. Keyomarsi, Richard G. Moran, Folinic acid augmentation of the effects of fluoropyrimidines on murine and human leukemic cells. Cancer Research. ,vol. 46, pp. 5229- 5235 ,(1986)
David R. Cox, Regression Models and Life-Tables Springer Series in Statistics. ,vol. 34, pp. 527- 541 ,(1992) , 10.1007/978-1-4612-4380-9_37
V. S. Gupta, W. L. Sawicki, J. R. Bertino, C. A. Lindquist, Schedule-dependent Antitumor Effects of Methotrexate and 5-Fluorouracil Cancer Research. ,vol. 37, pp. 327- 328 ,(1977)
D Machover, E Goldschmidt, P Chollet, G Metzger, J Zittoun, J Marquet, J M Vandenbulcke, J L Misset, L Schwarzenberg, J B Fourtillan, Treatment of advanced colorectal and gastric adenocarcinomas with 5-fluorouracil and high-dose folinic acid. Journal of Clinical Oncology. ,vol. 4, pp. 685- 696 ,(1986) , 10.1200/JCO.1986.4.5.685
Laskin Jd, Evans Rm, Hakala Mt, Effect of excess folates and deoxyinosine on the activity and site of action of 5-fluorouracil. Cancer Research. ,vol. 41, pp. 3288- 3295 ,(1981)
E. L. Kaplan, Paul Meier, Nonparametric Estimation from Incomplete Observations Springer Series in Statistics. ,vol. 53, pp. 319- 337 ,(1992) , 10.1007/978-1-4612-4380-9_25