Cytotoxic Chemotherapy for Metastatic Colorectal Cancer
作者： M.Wasif Saif , Richard Kim , Edward Chu
DOI: 10.1007/978-1-59745-215-1_4
关键词: Oncology 、 Topoisomerase-I Inhibitor 、 Capecitabine 、 Colorectal cancer 、 CA15-3 、 Fluorouracil 、 Medicine 、 Irinotecan 、 Internal medicine 、 Oxaliplatin 、 Cancer
摘要: Over the past 10 yr, significant advances have been made with respect to new anticancer agents for metastatic colorectal cancer. These compounds include topoisomerase I inhibitor irinotecan, third-generation platinum analog oxaliplatin, and oral fluoropyrimidine capecitabine, in addition mainstay, fluorouracil. The use of these is discussed this chapter.
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sci-hub.st 参考文章(41)
B. F. El-Rayes, A. F. Shields, U. Vaishampayan, L. Heilbrun, T. Bekaii-Saab, M. M. Zalupski, P. A. Philip, Phase II study of capecitabine, irinotecan, and celecoxib in advanced colorectal cancer Journal of Clinical Oncology. ,vol. 22, pp. 3766- 3766 ,(2004) , 10.1200/JCO.2004.22.14_SUPPL.3766
A. Grothey, K. Jordan, O. Kellner, C. Constantin, G. Dietrich, H. Kroening, L. Mantovani, C. Schlichting, H. Forstbauer, H.-J. Schmoll, Capecitabine/ irinotecan (CapIri) and capecitabine/oxaliplatin (CapOx) are active second-line protocols in patients with advanced colorectal cancer (ACRC) after failure of first-line combination therapy: Results of a randomized phase II study Journal of Clinical Oncology. ,vol. 22, pp. 3534- 3534 ,(2004) , 10.1200/JCO.2004.22.90140.3534
M A Poon, M J O'Connell, C G Moertel, H S Wieand, S A Cullinan, L K Everson, J E Krook, J A Mailliard, J A Laurie, L K Tschetter, Biochemical modulation of fluorouracil: evidence of significant improvement of survival and quality of life in patients with advanced colorectal carcinoma. Journal of Clinical Oncology. ,vol. 7, pp. 1407- 1418 ,(1989) , 10.1200/JCO.1989.7.10.1407
Modulation of fluorouracil by leucovorin in patients with advanced colorectal cancer: an updated meta-analysis. Journal of Clinical Oncology. ,vol. 22, pp. 3766- 3775 ,(2004) , 10.1200/JCO.2004.03.104
T R Buroker, M J O'Connell, H S Wieand, J E Krook, J B Gerstner, J A Mailliard, P L Schaefer, R Levitt, C G Kardinal, D H Gesme, Randomized comparison of two schedules of fluorouracil and leucovorin in the treatment of advanced colorectal cancer. Journal of Clinical Oncology. ,vol. 12, pp. 14- 20 ,(1994) , 10.1200/JCO.1994.12.1.14
Paulo M. Hoff, Rafat Ansari, Gerald Batist, John Cox, Walter Kocha, Mario Kuperminc, Jean Maroun, David Walde, Charles Weaver, Evelyn Harrison, Hans U. Burger, Bruno Osterwalder, Alfred O. Wong, Ralf Wong, Comparison of Oral Capecitabine Versus Intravenous Fluorouracil Plus Leucovorin as First-Line Treatment in 605 Patients With Metastatic Colorectal Cancer: Results of a Randomized Phase III Study Journal of Clinical Oncology. ,vol. 19, pp. 2282- 2292 ,(2001) , 10.1200/JCO.2001.19.8.2282
Udo Vanhoefer, Andreas Harstrick, Wolf Achterrath, Shousong Cao, Siegfried Seeber, Youcef M. Rustum, Irinotecan in the Treatment of Colorectal Cancer: Clinical Overview Journal of Clinical Oncology. ,vol. 19, pp. 1501- 1518 ,(2001) , 10.1200/JCO.2001.19.5.1501
A de Gramont, J F Bosset, C Milan, P Rougier, O Bouché, P L Etienne, F Morvan, C Louvet, T Guillot, E François, L Bedenne, Randomized trial comparing monthly low-dose leucovorin and fluorouracil bolus with bimonthly high-dose leucovorin and fluorouracil bolus plus continuous infusion for advanced colorectal cancer: a French intergroup study. Journal of Clinical Oncology. ,vol. 15, pp. 808- 815 ,(1997) , 10.1200/JCO.1997.15.2.808
A De Gramont, A Cervantes, T Andre, A Figer, G Lledo, M Flesch, L Mineur, G Russ, E Quinaux, P-L Etienne, None, OPTIMOX study: FOLFOX 7/LV5FU2 compared to FOLFOX 4 in patients with advanced colorectal cancer Journal of Clinical Oncology. ,vol. 22, pp. 3525- 3525 ,(2004) , 10.1200/JCO.2004.22.90140.3525
Emilio Bajetta, Maria Di Bartolomeo, Luigi Mariani, Antonio Cassata, Salvatore Artale, Sergio Frustaci, Graziella Pinotti, Andrea Bonetti, Ignazio Carreca, Guido Biasco, Luigi Bonaglia, Giovanni Marini, Antonio Iannelli, Diego Cortinovis, Ermina Ferrario, Elena Beretta, Antonio Lambiase, Roberto Buzzoni, Italian Trials in Medical Oncology (ITMO) Group, Randomized multicenter Phase II trial of two different schedules of irinotecan combined with capecitabine as first-line treatment in metastatic colorectal carcinoma Cancer. ,vol. 100, pp. 279- 287 ,(2004) , 10.1002/CNCR.11910