作者: Karen E. A. Burns , Aldo T. Iacono
DOI: 10.1097/01.TP.0000114308.94880.2A
关键词: Cause of death 、 Surgery 、 Bronchiolitis obliterans 、 Pulmonary embolism 、 Transplantation 、 Bacterial pneumonia 、 Lung transplantation 、 Autopsy 、 Internal medicine 、 Medicine 、 Respiratory disease
摘要: Introduction. Postmortem reports highlight the importance of factors that individually or collectively limit survival. The prevalence pulmonary embolism (PE) at autopsy in lung-transplant recipients has not been characterized previously. Objective. We aimed to describe PE, infection, and acute chronic rejection their respective contributions death according survival posttransplantation. Methods. retrospectively reviewed 126 performed lung-and heart–lung-transplant between June 1990 September 2002. Results. PE was identified 34 (27.0%) lung- recipients. autopsy-established highest, 36.4%, early group (1–30 days) compared with 20.0% 23.8% intermediate (31–365 late (>365 groups, respectively. Although fungal viral pneumonia were noted most frequently bacterial 32% 45% autopsies over posttransplant period. Acute cellular bronchiolitis obliterans present 29.5% 2.3%, 40.0% 17.5%, 35.7% 42.9% patients early, intermediate, frequent cause infection. Conclusions. highest mechanically ventilated postoperative Heart-lung lower risk for double- single-lung may be an under-appreciated complication contributing respiratory failure