Late Sudden Unexpected Deaths in Hospitalized Infants With Bronchopulmonary Dysplasia

摘要: • To determine the relative contribution of sudden death as a cause late inpatient mortality in newborns after prolonged mechanical ventilation, we reviewed charts 348 patients who received ventilation assistance and were admitted to neonatal intensive care unit during 26-month period. The overall rate for these was 25%, with 88% (77/88) deaths occurring within 30 days birth. Eleven infants died more than 60 ventilation. Seven sudden, unexpected inhospital deaths. Sudden occurred at mean (uncorrected) age 12 months (range, 4 27 months), periods when appeared be stable or clinically improving, unrelated recent respiratory exacerbations, despite prompt resuscitative efforts. Four still required had tracheostomies time death. All chronic hypercarbia (50 mm Hg) an elevated serum bicarbonate level (30 mmol/L), but not hyponatremia, hypochloremia (80 alkalemia. Left right ventricular hypertrophy, multiple drug therapy, recurrent cyanotic episodes, frequent unexplained fevers common. In comparison 17 bronchopulmonary dysplasia survivors longer group frequently left hypertrophy combination theophylline anhydrous β-adrenergic agonist therapy. We report that can occur severe in-hospital cardiopulmonary monitoring rapid institution resuscitation, is significant receive therapy 2 months. ( AJDC . 1989;143:815-819)