Oxygen desaturation complicates feeding in infants with bronchopulmonary dysplasia after discharge

摘要: Recurrent episodes of hypoxemia may affect the growth, cardiac function, neurologic outcome, and survival infants with bronchopulmonary dysplasia (BPD). As oral feeding might stress these by compromising pulmonary function even after hospital discharge, we measured oxygen saturation (SaO2) via pulse oximetry before, during initial 10 minutes of, immediately in 11 patients BPD, 12 very low birth weight infants, 23 healthy full-term infants. All BPD had been previously discharged from weaning supplemental oxygen. Studies were done at a mean postconceptional age 43 weeks while fed home one their parents. Levels SaO2 for three groups comparable before feeds. After feeding, significantly lower levels (84 +/- 8% [SD] vs 93 4% 3%, respectively; P less than .01). They also spent more time an 90% (64 34% 27 33% 22 20% term group; .01) greater 80% (37 28% 4 10% 8%, Desaturation was related to larger volume faster intake feeding. Thus, data indicate that desaturation remains recurrent problem survivors discharge.(ABSTRACT TRUNCATED AT 250 WORDS)