作者: Johan F. Vansteenkiste , Sigrid S. Stroobants
DOI: 10.1016/S1556-0864(15)31516-1
关键词: Lung cancer screening 、 Positron emission tomography 、 In patient 、 Lung cancer 、 Tomography 、 Medicine 、 Radiation therapy 、 Mediastinoscopy 、 Differential diagnosis 、 Radiology
摘要: Abstract: In the past 10 years, positron emission tomography (PET), usually with 18 F-fluoro-2-deoxy-D-glucose (FDG), has become an important imaging modality in patients lung cancer. FDG-PET is recommended for diagnosis of indeterminate pulmonary nodules, which it significantly more accurate than computed (CT) distinction between benign and malignant lesions. A large body evidence convincingly demonstrates that loco-regional lymph node staging by (in correlation CT images) superior to alone, a negative predictive value equal or even mediastinoscopy. also improves extrathoracic through detection lesions missed at conventional characterization remain equivocal on imaging. Ongoing studies now concentrate advanced clinical applications, such as planning radiotherapy, response evaluation after induction therapy, early recurrence, use cancer screening. Technical innovations, PET cameras better spatial resolution, new radiopharmaceutical probes study applications molecular biology hold promise future refinements this field.