Lésions d’ischémie-reperfusion en transplantation pulmonaire

摘要: Lung ischemia-reperfusion is characterized by diffuse alveolar damage arising from the first hours after transplantation. The etiology of primary graft dysfunction in lung ischemia-reperfusion. It burdened an important morbi-mortality. increases oxidative stress, inactivates sodium pump, intracellular calcium, leads to cellular death and liberation pro-inflammatory mediators. Researches relative reduction injuries are numerous but few them found a place common clinical practice, because insufficient level proofs. Ex vivolung evaluation suitable technique order evaluate therapeutics supposed limit injuries.