Diabetes mellitus and renal failure: Prevention and management

作者: Mahmoud Rafieian-Kopaei , Hamid Nasri

DOI: 10.4103/1735-1995.172845

关键词: MetforminLactic acidosisGlycemicDiabetes mellitusType 2 diabetesRepaglinideType 1 diabetesGastroenterologyPostprandialInternal medicineMedicineEndocrinology

摘要: Nowadays, diabetes mellitus (DM) and hypertension are considered as the most common causes of end-stage renal disease (ESRD). In this paper, other than presenting role DM in ESRD, glucose metabolism management hyperglycemia these patients reviewed. Although several large studies there was no significant relationship found between tight glycemic control survival ESRD patients, it is recommended that be main therapeutic goal treatment to prevent damage organs. Glycemic perfect when fasting blood sugar less 140 mg/dL, 1-h postprandial 200 glycosylated hemoglobin (HbA1c) 6-7 with type 1 7-8 2 diabetes. Administration metformin should avoided chronic failure (CRF) because lactic acidosis, potentially fatal complication metformin, but glipizide repaglinide seem good choices.

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