Pyrene as a fluorescent probe for DNA base radicals

作者: Robert Huber , Torsten Fiebig , Hans-Achim Wagenknecht

DOI: 10.1039/B305732A

关键词: ChemistryPyrimidineRadicalEmission spectrumFluorescencePhotochemistryDNAPyreneBase (chemistry)Purine

摘要: The steady-state emission spectra of 5-(1-pyrenyl)-modified pyrimidine and 8-(1-pyrenyl)-modified purine nucleosides in water at different pH values provide important information about the acidity or basicity photochemically generated DNA base radicals which are key intermediates DNA-mediated charge transport processes.

参考文章(20)
Steen Steenken, Slobodan V. Jovanovic, How Easily Oxidizable Is DNA? One-Electron Reduction Potentials of Adenosine and Guanosine Radicals in Aqueous Solution Journal of the American Chemical Society. ,vol. 119, pp. 617- 618 ,(1997) , 10.1021/JA962255B
Xifeng Li, Zhongli Cai, Michael D. Sevilla, DFT Calculations of the Electron Affinities of Nucleic Acid Bases: Dealing with Negative Electron Affinities Journal of Physical Chemistry A. ,vol. 106, pp. 1596- 1603 ,(2002) , 10.1021/JP013337B
Thomas L. Netzel, Min Zhao, Kambiz Nafisi, Jeb Headrick, Matthew S. Sigman, Bruce E. Eaton, Photophysics of 2'-Deoxyuridine (dU) Nucleosides Covalently Substituted with Either 1-Pyrenyl or 1-Pyrenoyl: Observation of Pyrene-to-Nucleoside Charge-Transfer Emission in 5-(1-Pyrenyl)-dU Journal of the American Chemical Society. ,vol. 117, pp. 9119- 9128 ,(1995) , 10.1021/JA00141A002
Nadrian C. Seeman, Nucleic Acid Nanostructures and Topology Angewandte Chemie International Edition. ,vol. 37, pp. 3220- 3238 ,(1998) , 10.1002/(SICI)1521-3773(19981217)37:23<3220::AID-ANIE3220>3.0.CO;2-C
Christoph Behrens, Lars T. Burgdorf, Anja Schwögler, Thomas Carell, Weak Distance Dependence of Excess Electron Transfer in DNA Angewandte Chemie International Edition. ,vol. 41, pp. 1763- 1766 ,(2002) , 10.1002/1521-3773(20020517)41:10<1763::AID-ANIE1763>3.0.CO;2-M
Bernd Giese, Long-Distance Electron Transfer Through DNA Annual Review of Biochemistry. ,vol. 71, pp. 51- 70 ,(2002) , 10.1146/ANNUREV.BIOCHEM.71.083101.134037
Christof M. Niemeyer, Michael Adler, Nanomechanical Devices Based on DNA Angewandte Chemie International Edition. ,vol. 41, pp. 3779- 3783 ,(2002) , 10.1002/1521-3773(20021018)41:20<3779::AID-ANIE3779>3.0.CO;2-F
Danny Porath, Alexey Bezryadin, Simon de Vries, Cees Dekker, Direct measurement of electrical transport through DNA molecules Nature. ,vol. 403, pp. 635- 638 ,(2000) , 10.1038/35001029
Elizabeth M Boon, Jacqueline K Barton, Charge transport in DNA. Current Opinion in Structural Biology. ,vol. 12, pp. 320- 329 ,(2002) , 10.1016/S0959-440X(02)00327-5