Anti-Müllerian hormone: a marker for oocyte quantity, oocyte quality and embryo quality?
作者： S Lie Fong , EB Baart , E Martini , I Schipper , JA Visser
DOI: 10.1016/S1472-6483(10)60480-4
关键词: Embryo quality 、 Embryo 、 Follicle-stimulating hormone 、 Semen 、 In vitro fertilisation 、 Andrology 、 Ovarian reserve 、 Oocyte 、 Biology 、 Internal medicine 、 Endocrinology 、 Anti-Müllerian hormone
摘要: Serum anti-Mullerian hormone (AMH) concentrations decline with increasing age and constitute a sensitive marker for ovarian ageing. In addition, basal serum AMH predict response during IVF cycles. Concomitantly, oocyte quantity embryo quality decrease advancing age. Hence, it was postulated that in constitutes quality. Women aged 37 years younger regular menstrual cycles, normal body mass index partners semen parameters were randomly assigned to either standard or mild stimulation protocol treatment. Blood samples drawn at cycle day 3 the of human chorionic gonadotrophin administration. Embryo assessed using morphology score preimplantation genetic screening. on correlated number oocytes retrieved both groups. after stimulation, but not conventional stimulation. chromosomal competence embryos correlated. is predictive However, lack consistent correlation aneuploidy rate favour direct relationship between
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