Curcumin produces antidepressant effects via activating MAPK/ERK-dependent brain-derived neurotrophic factor expression in the amygdala of mice.

作者: Lin Zhang , Tianyuan Xu , Shuang Wang , Lanqing Yu , Dexiang Liu

DOI: 10.1016/J.BBR.2012.07.019

关键词: AntidepressantBehavioural despair testAnimal models of depressionBrain-derived neurotrophic factorAmygdalaCurcuminKinasePharmacologyChemistryMAPK/ERK pathway

摘要: The potential antidepressant effects of curcumin have been demonstrated in various animal models of depression, however, there is little information regarding the site and mechanisms …

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