A chemically modified electrode with hydroquinone derivative based on carbon nanoparticles for simultaneous determination of isoproterenol, uric acid, folic acid and tryptophan

摘要: A nanostructure electrochemical sensor with a carbon paste electrode has been used to study the electrocatalytic oxidation of isoproterenol (IP) in presence uric acid, folic acid and tryptophan. In this work nanoparticles (CNPs) 7-(3,4-dihydroxyphenyl)-10,10-dimethyl-9,10,11,12-tetrahydrobenzo[c]acridin-9 (7H)-one (DDTA) were for investigation behaviour IP. An apparent charge transfer rate constant ks = 1.99 s−1, coefficient α 0.51, electron between modifier calculated. optimum pH (pH 9.0), IP at modified occurs potential about 298 mV less positive than unmodified electrode. The catalytic (k 134.28 M−1 s−1) diffusion (D 3.7 × 10−5 cm2 calculated by chronoamperometry. Differential pulse voltammetry (DPV) exhibited two linear dynamic ranges 0.25 20.0 μM 2000.0 There was decrease sensitivity second segment due kinetic limitations. Also, determine (UA), (FA) tryptophan (TRY) differential voltammetry. Simultaneous determination these four compounds performed on proposed first time. This from an ampoule sample. detection limit as 0.075 μM.