作者: Iria Bravo , Mónica Revenga-Parra , Karina Weber , Jürgen Popp , Félix Pariente
DOI: 10.1016/J.SNB.2018.03.170
关键词: Oxide 、 Chemistry 、 Schiff base 、 Combinatorial chemistry 、 Hydroquinone 、 Biosensor 、 Electrochemistry 、 Nanomaterials 、 Quinone 、 Graphene
摘要: Abstract One-step approach to simultaneously reduce and modify graphene oxide (GO) using N,N’-Bis(3,4-dihydroxybenzylidene)-1,2-diaminobenzene Schiff base ligand (3,4DHS), in order obtain functionalized reduced (rGO-DHS), is described. Once the novel hybrid nanomaterial was characterized by spectroscopic electrochemical techniques, confirming presence of characteristic quinone/hydroquinone moieties, it has been combined with lactate oxidase (LOx) develop a sensitive selective reagentless biosensor. The resulting biosensing device shows very good analytical performance detection determination limits 2.9 9.7 μM, respectively. RSD for three different devices lower than 9%. operational stability more one month. applicability demonstrated direct l -lactate content white wine.