HCV and Oxidative Stress in the Liver

作者: Alexander Ivanov , Birke Bartosch , Olga Smirnova , Maria Isaguliants , Sergey Kochetkov

DOI: 10.3390/V5020439

关键词: ImmunologyHepatitis C virusChronic liver diseaseCirrhosisPopulationInterferonBiologyHepatitis CHepatocellular carcinomaOxidative stress

摘要: … , and oxidative stress contributes to many of them. To date it has been accepted that HCV-induced oxidative stress leads to liver injury. For example, ROS levels, measured in liver using …

参考文章(220)
Naoki Fujita, Ryosuke Sugimoto, Masaki Takeo, Naohito Urawa, Rumi Mifuji, Hideaki Tanaka, Yoshinao Kobayashi, Motoh Iwasa, Shozo Watanabe, Yukihiko Adachi, Masahiko Kaito, Hepcidin expression in the liver: relatively low level in patients with chronic hepatitis C. Molecular Medicine. ,vol. 13, pp. 97- 104 ,(2007) , 10.2119/2006-00057.FUJITA
Roberto Nocente, Nicolò Gentiloni Silveri, Mauro Ceccanti, Giovanni Gasbarrini, Giovanni Cammarota, Giuliano Bertazzoni, HCV infection and extrahepatic manifestations Hepato-gastroenterology. ,vol. 50, pp. 1149- 1154 ,(2003)
David Brandhagen, Lorenzo Rossaro, Christopher L. Bowlus, Mary F. Burritt, Christopher A. Aoki, Rajendra Ramsamooj, Liver hepcidin mRNA correlates with iron stores, but not inflammation, in patients with chronic hepatitis C. Journal of Clinical Gastroenterology. ,vol. 39, pp. 71- 74 ,(2005)
Christopher Koh, Qisheng Li, Jake Liang, Hepatitis C virus. Clinical virology. pp. 1215- 1240 ,(2009) , 10.1128/9781555819439.CH54
Linbai Ye, Zhenghui Wu, Wei Jing, Yi Zheng, Bo Gao, Xiaojun Yang, Li Ye, Lingbao Kong, Hepatitis C virus non-structural protein NS4B can modulate an unfolded protein response. Journal of Microbiology. ,vol. 43, pp. 529- 536 ,(2005)
Radhika Desikan, John Hancock, Steven Neill, Reactive Oxygen Species as Signalling Molecules Blackwell Publishing Ltd. pp. 169- 196 ,(2007) , 10.1002/9780470988565.CH7
R. K. Gieseler, G. Marquitan, M. Schlattjan, J.-P. Sowa, L. P. Bechmann, J. Timm, M. Roggendorf, G. Gerken, S. L. Friedman, A. Canbay, Hepatocyte apoptotic bodies encasing nonstructural HCV proteins amplify hepatic stellate cell activation: implications for chronic hepatitis C Journal of Viral Hepatitis. ,vol. 18, pp. 760- 767 ,(2011) , 10.1111/J.1365-2893.2010.01362.X
Mie Ando, Masaaki Korenaga, Keisuke Hino, Masanori Ikeda, Nobuyuki Kato, Sohji Nishina, Isao Hidaka, Isao Sakaida, Mitochondrial electron transport inhibition in full genomic hepatitis C virus replicon cells is restored by reducing viral replication. Liver International. ,vol. 28, pp. 1158- 1166 ,(2008) , 10.1111/J.1478-3231.2008.01720.X
Nancy C. Andrews, Iron homeostasis: insights from genetics and animal models Nature Reviews Genetics. ,vol. 1, pp. 208- 217 ,(2000) , 10.1038/35042073
T. Wang, R. V. Campbell, M. K. Yi, S. M. Lemon, S. A. Weinman, Role of Hepatitis C virus core protein in viral-induced mitochondrial dysfunction Journal of Viral Hepatitis. ,vol. 17, pp. 784- 793 ,(2010) , 10.1111/J.1365-2893.2009.01238.X