Childhood polymyositis/ dermatomyositis
作者： Lynne J. Roberts , Chester W. Fink
DOI: 10.1016/0738-081X(88)90048-X
关键词: Immunity 、 Pathogenesis 、 Disease 、 Immunology 、 Polymyositis-Dermatomyositis 、 Medicine 、 Pathology
摘要: Children with PM/DM differ in many respects from adults PM/DM. The most characteristic and distinctive feature is the presence of a widespread vasculopathy. Although pathogenesis unknown, roles for both humoral cell-mediated immunity have been proposed. Most intriguing evidence viral agent that capable precipitating an ongoing, immunologically mediated reaction damaging muscles endothelial cells. Much remains to be discovered, however, regarding this disease.
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