Screening for cervical neoplasia in a developing country utilizing cytology, cervicography and the acetic acid test.

摘要: Abstract Objective: To compare three screening tests for cervical neoplasia. Method: Women (6301) were screened simultaneously with cytology, cervicography and the acetic acid test (AAT). Biopsies taken from acetowhite lesions every fifth seemingly normal cervix. Positive cases (both at histology) referred colposcopy. The histology results served as golden standard. Results: Cytology was positive in 1.7% of cases, 10.7% AAT 17.8%. sensitivity cytology 19.3%, 41.8% 49.4%. Corresponding specificities 99.3%, 78.8% 48.5%. In 23% biopsies showing intraepithelial neoplasia (grade I–III), all negative. By combining tests, a 76.9% achieved. Conclusion: alone is not great enough implementing developing country where programs are often inadequate. Screening combination once or few times per woman's life, more acceptable alternative since it allows less events without sacrifying sensitivity.