High-extinction VIPA-based Brillouin spectroscopy of turbid biological media
作者： Antonio Fiore , Jitao Zhang , Peng Shao , Seok Hyun Yun , Giuliano Scarcelli
DOI: 10.1063/1.4948353
关键词: Extinction (optical mineralogy) 、 Microscopy 、 Brillouin Spectroscopy 、 Spectrometer 、 Materials science 、 Interferometry 、 Spectral line 、 Brillouin zone 、 Optics 、 Fabry–Pérot interferometer
摘要: Brillouin microscopy has recently emerged as powerful technique to characterize the mechanical properties of biological tissue, cell and biomaterials. However, potential is currently limited transparent samples, because spectrometers do not have sufficient spectral extinction reject predominant non-Brillouin scattered light turbid media. To overcome this issue, we developed a spectrometer composed two VIPA stages multi-pass Fabry-Perot interferometer. The etalon acts an ultra-narrow band-pass filter for with high low loss. We report background-free spectra from Intralipid solutions up 100 microns deep within chicken muscle tissue.
arxiv.org
sci-hub.se 参考文章(9)
Yasuo Minami, Keiji Sakai, Ripplon on high viscosity liquid. Review of Scientific Instruments. ,vol. 80, pp. 014902- ,(2009) , 10.1063/1.3072604
Yasuo Minami, Takeshi Yogi, Keiji Sakai, Millisecond Brillouin scattering spectroscopy Applied Physics Letters. ,vol. 93, pp. 161107- ,(2008) , 10.1063/1.3002301
A. V. Svanidze, V. P. Romanov, S. G. Lushnikov, Anomalous behavior of Brillouin light scattering at thermal denaturation of lysozyme Jetp Letters. ,vol. 93, pp. 409- 414 ,(2011) , 10.1134/S0021364011070113
Giuliano Scarcelli, Seok Hyun Yun, Confocal Brillouin microscopy for three-dimensional mechanical imaging Nature Photonics. ,vol. 2, pp. 39- 43 ,(2008) , 10.1038/NPHOTON.2007.250
Giuliano Scarcelli, William J Polacheck, Hadi T Nia, Kripa Patel, Alan J Grodzinsky, Roger D Kamm, Seok Hyun Yun, Noncontact three-dimensional mapping of intracellular hydromechanical properties by Brillouin microscopy Nature Methods. ,vol. 12, pp. 1132- 1134 ,(2015) , 10.1038/NMETH.3616
Giuliano Scarcelli, Seok Hyun Yun, Multistage VIPA etalons for high-extinction parallel Brillouin spectroscopy Optics Express. ,vol. 19, pp. 10913- 10922 ,(2011) , 10.1364/OE.19.010913
Itay Remer, Alberto Bilenca, Background-free Brillouin spectroscopy in scattering media at 780 nm via stimulated Brillouin scattering. Optics Letters. ,vol. 41, pp. 926- 929 ,(2016) , 10.1364/OL.41.000926
M. Čopič, M. Zgonik, On multi-pass Fabry-Perot interferometer Optics Communications. ,vol. 41, pp. 310- 314 ,(1982) , 10.1016/0030-4018(82)90403-5
W.F. Cheong, S.A. Prahl, A.J. Welch, A review of the optical properties of biological tissues IEEE Journal of Quantum Electronics. ,vol. 26, pp. 2166- 2185 ,(1990) , 10.1109/3.64354