Demographic Characteristics, Survival and Prognostic Factors for Mortality in Cats with Primary Immune-Mediated Hemolytic Anemia.

摘要: Background Immune-mediated hemolytic anemia (IMHA) is uncommon in cats, but may result severe disease. Demographic predispositions for development of the disease and prognostic factors mortality have not been investigated previously. Hypothesis/Objectives To explore possible demographic primary IMHA cats to investigate mortality. Animals 107 client-owned with IMHA, which 72 had 35 secondary 9,194 control cats. Methods Data were collected retrospectively from records defined by presence concurrent autoagglutination, ghost cells without oxidative damage on fresh blood smear, positive titer a direct antiglobulin test, or evidence phagocytosis erythroid precursors bone marrow. Odds ratios calculated assess risk different groups Cox proportional hazards analysis was conducted evaluate factors. Results No sex breed predisposition identified comparison age range 2.1–5.9 years predisposed. Higher total bilirubin concentration significant negative higher lymphocyte numbers serum globulin multivariable model. Conclusions Clinical Importance Young adult more likely develop than other groups, no apparent male this study, contrary previous reports. Several identified, be helpful guiding clinical practice future.