Molecular architecture of native fibronectin fibrils

作者: Susanna Maria Früh , Ingmar Schoen , Jonas Ries , Viola Vogel

DOI: 10.1038/NCOMMS8275

关键词: Optical imagingProtein structureCell biologyChemistryExtracellular matrixSupporting cellFibronectinsAdhesionFibronectinFibril

摘要: Fibronectin fibres are an important component of the extracellular matrix, supporting cell adhesion, growth and migration. Here authors combine site-specific protein labelling with single-molecule localization microscopy to provide detailed insights into molecular organization native fibronectin fibrils.

参考文章(69)
Richard O. Hynes, Kenneth M. Yamada, Extracellular matrix biology Cold Spring Harbor Laboratory Press. ,(2012)
M.A. Chernousov, F.J. Fogerty, V.E. Koteliansky, D.F. Mosher, Role of the I-9 and III-1 modules of fibronectin in formation of an extracellular fibronectin matrix. Journal of Biological Chemistry. ,vol. 266, pp. 10851- 10858 ,(1991) , 10.1016/S0021-9258(18)99097-6
P.J. McKeown-Longo, D.C. Hocking, J. Sottile, Fibronectin's III-1 module contains a conformation-dependent binding site for the amino-terminal region of fibronectin. Journal of Biological Chemistry. ,vol. 269, pp. 19183- 19191 ,(1994) , 10.1016/S0021-9258(17)32292-5
J.A. McDonald, B.J. Quade, T.J. Broekelmann, R. LaChance, K. Forsman, E. Hasegawa, S. Akiyama, Fibronectin's cell-adhesive domain and an amino-terminal matrix assembly domain participate in its assembly into fibroblast pericellular matrix. Journal of Biological Chemistry. ,vol. 262, pp. 2957- 2967 ,(1987) , 10.1016/S0021-9258(18)61453-X
K M Aguirre, R J McCormick, J E Schwarzbauer, Fibronectin self-association is mediated by complementary sites within the amino-terminal one-third of the molecule. Journal of Biological Chemistry. ,vol. 269, pp. 27863- 27868 ,(1994) , 10.1016/S0021-9258(18)46866-4
J. Sottile, J. Schwarzbauer, J. Selegue, D.F. Mosher, Five type I modules of fibronectin form a functional unit that binds to fibroblasts and Staphylococcus aureus. Journal of Biological Chemistry. ,vol. 266, pp. 12840- 12843 ,(1991) , 10.1016/S0021-9258(18)98769-7
D.M. Peters, B.J. Dzamba, Arrangement of cellular fibronectin in noncollagenous fibrils in human fibroblast cultures Journal of Cell Science. ,vol. 100, pp. 605- 612 ,(1991) , 10.1242/JCS.100.3.605
Jacob W. J. Kerssemakers, E. Laura Munteanu, Liedewij Laan, Tim L. Noetzel, Marcel E. Janson, Marileen Dogterom, Assembly dynamics of microtubules at molecular resolution Nature. ,vol. 442, pp. 709- 712 ,(2006) , 10.1038/NATURE04928
André Lampe, Volker Haucke, Stephan J. Sigrist, Mike Heilemann, Jan Schmoranzer, Multi-colour direct STORM with red emitting carbocyanines Biology of the Cell. ,vol. 104, pp. 229- 237 ,(2012) , 10.1111/BOC.201100011
Alfredo Maqueda, José V. Moyano, Mercedes Hernández del Cerro, Donna M. Peters, Angeles Garcia-Pardo, The heparin III-binding domain of fibronectin (III4-5 repeats) binds to fibronectin and inhibits fibronectin matrix assembly. Matrix Biology. ,vol. 26, pp. 642- 651 ,(2007) , 10.1016/J.MATBIO.2007.06.001