Phylogenetic Methods Come of Age: Testing Hypotheses in an Evolutionary Context

作者: John P Huelsenbeck , Bruce Rannala

DOI: 10.1126/SCIENCE.276.5310.227

关键词: Phylogenetic treeContext (language use)Molecular evolutionBiologyField (computer science)Evolutionary biologyPhylogeneticsBase sequenceDNA sequencingBiological evolution

摘要: The use of molecular phylogenies to examine evolutionary questions has become commonplace with the automation DNA sequencing and availability efficient computer programs perform phylogenetic analyses. application simulation likelihood ratio tests hypotheses represents a recent methodological development in this field. Likelihood have enabled biologists address many biology that been difficult resolve past, such as whether host-parasite systems are cospeciating models substitution adequately explain observed sequences.

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