Imaging age-related cognitive decline: A comparison of diffusion tensor and magnetization transfer MRI.

作者: Francesca Schiavone , Rebecca Ann Charlton , Thomas Richard Barrick , Robin Guy Morris , Hugh Stephen Markus

DOI: 10.1002/JMRI.21572

关键词: Nuclear magnetic resonanceWhite matterMagnetization Transfer MRIDiffusion MRIAge-related cognitive declineCognitive declinePhysicsMagnetization transferNeuropsychology

摘要: DTI appears the most sensitive imaging parameter to determine age-related white matter damage. The stronger relationship with FA suggests that axonal damage is important in cognitive decline.

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