Single nucleotide polymorphisms in genes

作者: Stacey Bolk , George Q. Daley , Jeanette J. McCarthy , James S. Ireland , Eric S. Lander

DOI:

关键词: ThrombospondinGenePhenotypeClinical courseSingle-nucleotide polymorphismGeneticsNucleic acidBiologyHuman genomeGenetic analysis

摘要: The invention provides nucleic acid segments of the human genome, particularly from a gene, including polymorphic sites. Allele-specific primers and probes hybridizing to regions flanking or containing these sites are also provided. acids, used in applications such as phenotype correlations, forensics, paternity testing, medicine genetic analysis. A role for thrombospondin gene(s) vascular disease is disclosed. Use single nucleotide polymorphisms diagnosis, prediction clinical course treatment response, development therapeutics cell-culture-based animal models research

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