作者: Stacey Bolk , George Q. Daley , Jeanette J. McCarthy , James S. Ireland , Eric S. Lander
DOI:
关键词: Thrombospondin 、 Gene 、 Phenotype 、 Clinical course 、 Single-nucleotide polymorphism 、 Genetics 、 Nucleic acid 、 Biology 、 Human genome 、 Genetic analysis
摘要: The invention provides nucleic acid segments of the human genome, particularly from a gene, including polymorphic sites. Allele-specific primers and probes hybridizing to regions flanking or containing these sites are also provided. acids, used in applications such as phenotype correlations, forensics, paternity testing, medicine genetic analysis. A role for thrombospondin gene(s) vascular disease is disclosed. Use single nucleotide polymorphisms diagnosis, prediction clinical course treatment response, development therapeutics cell-culture-based animal models research