Evidence-based injury prediction data for the water temperature and duration of exposure for clinically relevant deep dermal scald injuries

摘要: Deep dermal burn injuries require extensive medical care; however, the water temperatures and durations of exposure that result in a severe scald injury are unknown. This study used porcine model to investigate time temperature threshold for clinically relevant deep both immersion (long duration) spill/splash (short events. Scald wounds were created on flanks anaesthetized juvenile large White pigs (27 kg). Acute tissue evaluations performed at 1 hour days 1, 3, 7 postburn (16 pigs) included: wound examination, biopsies, laser Doppler imaging. Up 20 combinations tested including: 50-60 °C 1-10 minutes (immersion); 60-90 °C 5 seconds (spill/splash). Burn conditions demonstrating mid-to-deep damage histologically followed 21 assess reepithelialize (eight pigs). Histologically, depth increased until day 3 postburn. Damage ≥75% dermis was associated with burns taking longer than weeks fully reepithelialize. For (5 seconds) scalds, ≥75 °C showed mid-dermis or deeper by 3; only from ≥85 °C not reepithelialized 21. scalds equivalent duration, 55 °C caused significantly 50 °C (p 10 minutes, 60 °C 60 seconds, 70 °C for > 15 seconds. research provides valuable evidence-based prediction data, which can be inform future prevention guidelines/legislation reduce risk support medicolegal opinions cases where an inflicted mechanism is alleged.