Study of the IR Spectra of the Saliva of Cancer Patients
作者： L. V. Bel’skaya , E. A. Sarf , I. A. Gundyrev
DOI: 10.1007/S10812-019-00762-Z
关键词: Breast cancer 、 Gastroenterology 、 Saliva 、 Cancer 、 Internal medicine 、 Lung 、 Infrared spectroscopy 、 Cancer recurrence 、 Lung cancer 、 Immune system 、 Medicine 、 Spectroscopy 、 Condensed matter physics
摘要: Feasibility has been demonstrated in principle for the diagnosis of lung and breast cancer by subjecting saliva to Fourier transform IR spectroscopy. Statistically significant differences patients are seen at 1070–1240 cm–1, while throughout entire range patients. The I1398/1454 I1240/1310 ratios were determined found be statistically reliable detecting pathology. Correlations intensities absorption bands these spectra with nonspecific biochemical parameters, which generally characterize greater intoxication as well suppression systems antioxidant protection immune response. A promising research trend involves use spectroscopy monitoring treatment recurrence.
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Biomarkers and surrogate endpoints: Preferred definitions and conceptual framework* Clinical Pharmacology & Therapeutics. ,vol. 69, pp. 89- 95 ,(2001) , 10.1067/MCP.2001.113989
Daping Sheng, Fangcheng Xu, Qiang Yu, Tingting Fang, Junjun Xia, Seruo Li, Xin Wang, None, A study of structural differences between liver cancer cells and normal liver cells using FTIR spectroscopy Journal of Molecular Structure. ,vol. 1099, pp. 18- 23 ,(2015) , 10.1016/J.MOLSTRUC.2015.05.054
Julian Ollesch, Margot Heinze, H. Michael Heise, Thomas Behrens, Thomas Brüning, Klaus Gerwert, It's in your blood: spectral biomarker candidates for urinary bladder cancer from automated FTIR spectroscopy. Journal of Biophotonics. ,vol. 7, pp. 210- 221 ,(2014) , 10.1002/JBIO.201300163
GI Dovbeshko, VI Chegel, N Ya Gridina, OP Repnytska, YM Shirshov, VP Tryndiak, IM Todor, GI Solyanik, None, Surface enhanced IR absorption of nucleic acids from tumor cells: FTIR reflectance study. Biopolymers. ,vol. 67, pp. 470- 486 ,(2002) , 10.1002/BIP.10165
Guo Jian, Zhou Songwen, Zhang Ling, Deng Qinfang, Zhang Jie, Tang Liang, Zhou Caicun, Prediction of epidermal growth factor receptor mutations in the plasma/pleural effusion to efficacy of gefitinib treatment in advanced non-small cell lung cancer. Journal of Cancer Research and Clinical Oncology. ,vol. 136, pp. 1341- 1347 ,(2010) , 10.1007/S00432-010-0785-Z
Xin Wang, Xiang Shen, Daping Sheng, Xianliang Chen, Xingcun Liu, None, FTIR spectroscopic comparison of serum from lung cancer patients and healthy persons Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. ,vol. 122, pp. 193- 197 ,(2014) , 10.1016/J.SAA.2013.11.049
Evgeny Bogomolny, Shmuel Argov, Shaul Mordechai, Mahmoud Huleihel, Monitoring of viral cancer progression using FTIR microscopy: a comparative study of intact cells and tissues. Biochimica et Biophysica Acta. ,vol. 1780, pp. 1038- 1046 ,(2008) , 10.1016/J.BBAGEN.2008.05.008
Jemma G. Kelly, Maneesh N. Singh, Helen F. Stringfellow, Michael J. Walsh, James M. Nicholson, Fariba Bahrami, Katherine M. Ashton, Mark A. Pitt, Pierre L. Martin-Hirsch, Francis L. Martin, Derivation of a subtype-specific biochemical signature of endometrial carcinoma using synchrotron-based Fourier-transform infrared microspectroscopy Cancer Letters. ,vol. 274, pp. 208- 217 ,(2009) , 10.1016/J.CANLET.2008.09.018
Norimasa Miura, Hiroshige Nakamura, Reina Sato, Tomoe Tsukamoto, Tomomi Harada, Shunsaku Takahashi, Youshin Adachi, Kohei Shomori, Akiko Sano, Yosuke Kishimoto, Hisao Ito, Junichi Hasegawa, Goshi Shiota, Clinical usefulness of serum telomerase reverse transcriptase (hTERT) mRNA and epidermal growth factor receptor (EGFR) mRNA as a novel tumor marker for lung cancer Cancer Science. ,vol. 97, pp. 1366- 1373 ,(2006) , 10.1111/J.1349-7006.2006.00342.X
Liu Dong, Xuejun Sun, Zhang Chao, Shiyun Zhang, Jianbao Zheng, Rajendra Gurung, Junkai Du, Jingsen Shi, Yizhuang Xu, Yuanfu Zhang, Jinguang Wu, None, Evaluation of FTIR spectroscopy as diagnostic tool for colorectal cancer using spectral analysis Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. ,vol. 122, pp. 288- 294 ,(2014) , 10.1016/J.SAA.2013.11.031