Integration of Friend murine leukemia virus into both alleles of the p53 oncogene in an erythroleukemic cell line.
作者： G G Hicks , M Mowat
DOI: 10.1128/JVI.62.12.4752-4755.1988
关键词: Virology 、 P53 oncogene 、 Molecular biology 、 Friend Murine Leukemia Virus 、 Regulation of gene expression 、 Biology 、 Nucleic acid thermodynamics 、 Allele 、 P53 protein 、 Coding region 、 Cell culture 、 Immunology 、 Insect Science 、 Microbiology
摘要: Abstract The Friend virus-transformed erythroleukemic cell line DP16-9B4 has undergone a complex rearrangement of the p53 oncogene and lacks any detectable expression protein. We report here characterization both alleles in this identify independent integrations murine leukemia virus sequences into coding region alleles.
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