作者: Erin J. Campbell , Andrew J. Lawrence , Christina J. Perry
DOI: 10.1007/S00213-018-4887-7
关键词: Clinical trial 、 Psychological intervention 、 Intensive care medicine 、 Milestone (project management) 、 Randomized controlled trial 、 Relapse prevention 、 Precision medicine 、 Alcohol use disorder 、 Cognitive behavioral therapy 、 Medicine
摘要: Alcohol use disorder is a complex syndrome with multiple treatment points including drug-induced pathology, withdrawal management, behavioral/cognitive strategies, and relapse prevention. These different components may be complicated by genotype phenotype. A huge milestone for the of alcohol across several countries in last 10 years was introduction practice guidelines integrating clinical expertise research evidence. provide summary interventions that have been shown to effective following rigorous replicated trials. Inspection these reveals good consistency, but little evidence progress approaches over past decade. In this mini-review, we discuss emerging treatments supplement or improve evidence-based are currently recommended. New medications, emergence digital technology, other novel such as transcranial magnetic stimulation all discussed reference already practice. We also consider how individual differences phenotype affect outcomes. Together improvements knowledge offers powerful tool designing personalized treatment, hence improving prognosis rehabilitation programs.