摘要: Personalized management of cardiovascular disorders (CVD), also referred to as personalized or precision cardiology in accordance with general principles medicine, is selection the best treatment for an individual patient. It involves integration various "omics" technologies such genomics and proteomics well other new nanobiotechnology. Molecular diagnostics biomarkers are important linking diagnosis therapy monitoring therapy. Because CVD involve perturbations large complex biological networks, a systems biology approach risk stratification may be used improving risk-estimating algorithms, modeling benefit helpful guiding choice intervention. Bioinformatics tools analyzing integrating amounts data from sources. considered during drug development, including methods targeted delivery clinical trials. Individualized recommendations consider multiple factors - genetic epigenetic patients' heart disease. Examples those chronic myocardial ischemia, failure, hypertension. Similar approaches can atrial fibrillation hypercholesterolemia, use anticoagulants. includes pharmacotherapy, surgery, lifestyle modifications, combinations thereof. Further progress understanding pathomechanism diseases identification causative at patient level will provide opportunities development cardiology. Application medicine improve care patients CVD.
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