Pharmacological inhibition of histone deacetylase reduces NADPH oxidase expression, oxidative stress and the progression of atherosclerotic lesions in hypercholesterolemic apolipoprotein E-deficient mice; potential implications for human atherosclerosis
作者： Simona-Adriana Manea , Mihaela-Loredana Vlad , Ioana Madalina Fenyo , Alexandra-Gela Lazar , Monica Raicu
DOI: 10.1016/J.REDOX.2019.101338
关键词:
摘要: … HDAC in mediating Nox up-regulation and oxidative stress in atherosclerosis is largely unknown. We hypothesized that HDAC … and the ensuing oxidative stress and inflammation in the …
sci-hub.se 参考文章(59)
Sarah Costantino, Peter Libby, Raj Kishore, Jean-Claude Tardif, Assam El-Osta, Francesco Paneni, Epigenetics and precision medicine in cardiovascular patients: from basic concepts to the clinical arena. European Heart Journal. ,vol. 39, pp. 4150- 4158 ,(2018) , 10.1093/EURHEARTJ/EHX568
Simona-Adriana Manea, Mihaela-Loredana Antonescu, Ioana Madalina Fenyo, Monica Raicu, Maya Simionescu, Adrian Manea, Epigenetic regulation of vascular NADPH oxidase expression and reactive oxygen species production by histone deacetylase-dependent mechanisms in experimental diabetes. Redox biology. ,vol. 16, pp. 332- 343 ,(2018) , 10.1016/J.REDOX.2018.03.011
Koji Uchida, Takahiro Shibata, Shinya Toyokuni, Bareket Daniel, Kamelija Zarkovic, Neven Zarkovic, Shlomo Sasson, Development of a novel monoclonal antibody against 4-hydroxy-2E,6Z-dodecadienal (4-HDDE)-protein adducts: Immunochemical application in quantitative and qualitative analyses of lipid peroxidation in vitro and ex vivo. Free Radical Biology and Medicine. ,vol. 124, pp. 12- 20 ,(2018) , 10.1016/J.FREERADBIOMED.2018.05.079
Weiqi Zhang, Moshi Song, Jing Qu, Guang-Hui Liu, Epigenetic Modifications in Cardiovascular Aging and Diseases. Circulation Research. ,vol. 123, pp. 773- 786 ,(2018) , 10.1161/CIRCRESAHA.118.312497
Micaela Gliozzi, Miriam Scicchitano, Francesca Bosco, Vincenzo Musolino, Cristina Carresi, Federica Scarano, Jessica Maiuolo, Saverio Nucera, Alessia Maretta, Sara Paone, Rocco Mollace, Stefano Ruga, Maria Caterina Zito, Roberta Macrì, Francesca Oppedisano, Ernesto Palma, Daniela Salvemini, Carolina Muscoli, Vincenzo Mollace, Modulation of Nitric Oxide Synthases by Oxidized LDLs: Role in Vascular Inflammation and Atherosclerosis Development. International Journal of Molecular Sciences. ,vol. 20, pp. 3294- ,(2019) , 10.3390/IJMS20133294
Aleksandr E. Vendrov, Arihiro Sumida, Chandrika Canugovi, Andrey Lozhkin, Takayuki Hayami, Nageswara R. Madamanchi, Marschall S. Runge, NOXA1-dependent NADPH oxidase regulates redox signaling and phenotype of vascular smooth muscle cell during atherogenesis Redox biology. ,vol. 21, pp. 101063- ,(2019) , 10.1016/J.REDOX.2018.11.021
V. Helfinger, K. Palfi, A. Weigert, K. Schröder, The NADPH Oxidase Nox4 Controls Macrophage Polarization in an NFκB-Dependent Manner Oxidative Medicine and Cellular Longevity. ,vol. 2019, pp. 3264858- ,(2019) , 10.1155/2019/3264858
Kewal K. Jain, Personalized Management of Cardiovascular Disorders Medical Principles and Practice. ,vol. 26, pp. 399- 414 ,(2017) , 10.1159/000481403
Wen Qin, Zi-Ying Wang, Fan Yi, Targeting histone deacetylases: perspectives for epigenetic-based therapy in cardio-cerebrovascular disease. Journal of Geriatric Cardiology. ,vol. 12, pp. 153- 164 ,(2015) , 10.11909/J.ISSN.1671-5411.2015.02.010
Flávia Rezende, Oliver Löwe, Valeska Helfinger, Kim-Kristin Prior, Maria Walter, Sven Zukunft, Ingrid Fleming, Norbert Weissmann, Ralf P. Brandes, Katrin Schröder, Unchanged NADPH Oxidase Activity in Nox1-Nox2-Nox4 Triple Knockout Mice: What Do NADPH-Stimulated Chemiluminescence Assays Really Detect? Antioxidants & Redox Signaling. ,vol. 24, pp. 392- 399 ,(2015) , 10.1089/ARS.2015.6314