The NADPH Oxidase Nox4 Controls Macrophage Polarization in an NFκB-Dependent Manner

作者: V. Helfinger , K. Palfi , A. Weigert , K. Schröder

DOI: 10.1155/2019/3264858

关键词:

摘要: … in macrophages is discussed controversially. Here, we show that macrophages besides a … in determining the polarization and the phenotype of macrophages. In bone marrow-derived …

参考文章(30)
Yaoyao Zhou, Tiantian Zhang, Xiaofei Wang, Xiaowei Wei, Yizhu Chen, Lingyu Guo, Junfeng Zhang, Changqian Wang, Curcumin Modulates Macrophage Polarization Through the Inhibition of the Toll-Like Receptor 4 Expression and its Signaling Pathways Cellular Physiology and Biochemistry. ,vol. 36, pp. 631- 641 ,(2015) , 10.1159/000430126
Satoshi Hirakawa, Rumiko Saito, Hiroshi Ohara, Ryuhei Okuyama, Setsuya Aiba, Dual Oxidase 1 Induced by Th2 Cytokines Promotes STAT6 Phosphorylation via Oxidative Inactivation of Protein Tyrosine Phosphatase 1B in Human Epidermal Keratinocytes Journal of Immunology. ,vol. 186, pp. 4762- 4770 ,(2011) , 10.4049/JIMMUNOL.1000791
Chao He, Alan J. Ryan, Shubha Murthy, A. Brent Carter, Accelerated development of pulmonary fibrosis via Cu,Zn-superoxide dismutase-induced alternative activation of macrophages. Journal of Biological Chemistry. ,vol. 288, pp. 20745- 20757 ,(2013) , 10.1074/JBC.M112.410720
Josef Anrather, Gianfranco Racchumi, Costantino Iadecola, NF-κB regulates phagocytic NADPH oxidase by inducing the expression of gp91phox Journal of Biological Chemistry. ,vol. 281, pp. 5657- 5667 ,(2006) , 10.1074/JBC.M506172200
Claudia Goettsch, Andrea Babelova, Olivia Trummer, Reinhold G. Erben, Martina Rauner, Stefan Rammelt, Norbert Weissmann, Valeska Weinberger, Sebastian Benkhoff, Marian Kampschulte, Barbara Obermayer-Pietsch, Lorenz C. Hofbauer, Ralf P. Brandes, Katrin Schröder, NADPH oxidase 4 limits bone mass by promoting osteoclastogenesis Journal of Clinical Investigation. ,vol. 123, pp. 4731- 4738 ,(2013) , 10.1172/JCI67603
Dale R. Balce, Baoquan Li, Euan R. O. Allan, Joanna M. Rybicka, Regina M. Krohn, Robin M. Yates, Alternative activation of macrophages by IL-4 enhances the proteolytic capacity of their phagosomes through synergistic mechanisms Blood. ,vol. 118, pp. 4199- 4208 ,(2011) , 10.1182/BLOOD-2011-01-328906
Lena Serrander, Laetitia Cartier, Karen Bedard, Botond Banfi, Bernard Lardy, Olivier Plastre, Andrzej Sienkiewicz, Lászlo Fórró, Werner Schlegel, Karl-Heinz Krause, NOX4 activity is determined by mRNA levels and reveals a unique pattern of ROS generation Biochemical Journal. ,vol. 406, pp. 105- 114 ,(2007) , 10.1042/BJ20061903
Nan Wang, Hongwei Liang, Ke Zen, Molecular Mechanisms That Influence the Macrophage M1–M2 Polarization Balance Frontiers in Immunology. ,vol. 5, pp. 614- 614 ,(2014) , 10.3389/FIMMU.2014.00614
Masuko Ushio-Fukai, Yoshimasa Nakamura, Reactive oxygen species and angiogenesis: NADPH oxidase as target for cancer therapy Cancer Letters. ,vol. 266, pp. 37- 52 ,(2008) , 10.1016/J.CANLET.2008.02.044
Katrin Schröder, Katalin Wandzioch, Ina Helmcke, Ralf P. Brandes, Nox4 Acts as a Switch Between Differentiation and Proliferation in Preadipocytes Arteriosclerosis, Thrombosis, and Vascular Biology. ,vol. 29, pp. 239- 245 ,(2009) , 10.1161/ATVBAHA.108.174219