Association of the Trp719Arg Polymorphism in Kinesin-Like Protein 6 With Myocardial Infarction and Coronary Heart Disease in 2 Prospective Trials: The CARE and WOSCOPS Trials

作者: Olga A. Iakoubova , Carmen H. Tong , Charles M. Rowland , Todd G. Kirchgessner , Bradford A. Young

DOI: 10.1016/J.JACC.2007.05.057

关键词: CohortMedicinePravastatinMyocardial infarctionOdds ratioSurgeryProportional hazards modelAbsolute risk reductionHazard ratioKIF6Internal medicine

摘要: Objectives : We asked whether 35 genetic polymorphisms, previously found to be associated with cardiovascular disease, were associated with myocardial infarction (MI) in the CARE (…

参考文章(44)
S. Santoso, T.J. Kunicki, H. Kroll, W. Haberbosch, A. Gardemann, Association of the platelet glycoprotein Ia C807T gene polymorphism with nonfatal myocardial infarction in younger patients. Blood. ,vol. 93, pp. 2449- 2453 ,(1999) , 10.1182/BLOOD.V93.8.2449
Stephan Seiler, Jochen Kirchner, Christian Horn, Athina Kallipolitou, Günther Woehlke, Manfred Schliwa, Cargo binding and regulatory sites in the tail of fungal conventional kinesin Nature Cell Biology. ,vol. 2, pp. 333- 338 ,(2000) , 10.1038/35014022
F.R. Rosendaal, D.S. Siscovick, S.M. Schwartz, B.M. Psaty, T.E. Raghunathan, H.L. Vos, A Common Prothrombin Variant (20210 G to A) Increases the Risk of Myocardial Infarction in Young Women Blood. ,vol. 90, pp. 1747- 1750 ,(1997) , 10.1182/BLOOD.V90.5.1747
Charalambos Antoniades, Dimitris Tousoulis, Carmen Vasiliadou, Elli Stefanadi, Kyriakoula Marinou, Christodoulos Stefanadis, Genetic Polymorphisms of Platelet Glycoprotein Ia and the Risk for Premature Myocardial Infarction Journal of the American College of Cardiology. ,vol. 47, pp. 1959- 1966 ,(2006) , 10.1016/J.JACC.2005.12.057
A. Hamsten, P. Eriksson, B. Kallin, F. M. van 't Hooft, P. Bavenholm, Allele-specific increase in basal transcription of the plasminogen-activator inhibitor 1 gene is associated with myocardial infarction Proceedings of the National Academy of Sciences of the United States of America. ,vol. 92, pp. 1851- 1855 ,(1995) , 10.1073/PNAS.92.6.1851
Shu Ye, Louise Dunleavey, Wendy Bannister, Lorna B Day, William Tapper, Andrew R Collins, Ian NM Day, Iain Simpson, Independent effects of the −219 G>T and ε 2/ ε 3/ ε 4 polymorphisms in the apolipoprotein E gene on coronary artery disease: The Southampton Atherosclerosis Study European Journal of Human Genetics. ,vol. 11, pp. 437- 443 ,(2003) , 10.1038/SJ.EJHG.5200983
Nilesh J. Samani, John R. Thompson, Laurence O'Toole, Kevin Channer, Kent L. Woods, A meta-analysis of the association of the deletion allele of the angiotensin-converting enzyme gene with myocardial infarction. Circulation. ,vol. 94, pp. 708- 712 ,(1996) , 10.1161/01.CIR.94.4.708
Aldons J. Lusis, Alan M. Fogelman, Gregg C. Fonarow, Genetic Basis of Atherosclerosis: Part I New Genes and Pathways Circulation. ,vol. 110, pp. 1868- 1873 ,(2004) , 10.1161/01.CIR.0000143041.58692.CC
A. Lupas, M. Van Dyke, J. Stock, Predicting coiled coils from protein sequences Science. ,vol. 252, pp. 1162- 1164 ,(1991) , 10.1126/SCIENCE.252.5009.1162
R. C. Elston, On Fisher's Method of Combining p-Values Biometrical Journal. ,vol. 33, pp. 339- 345 ,(1991) , 10.1002/BIMJ.4710330314