Intact language skills and semantic processing speed following the use of fractionated cranial irradiation therapy for the treatment of childhood medulloblastoma: A 4-year follow-up study

作者: Fiona M. Lewis , Bruce E. Murdoch

DOI: 10.1080/13554794.2010.509323

关键词: Semantic memoryCranial IrradiationDevelopmental psychologyPsychologyAcademic achievementInformation processingQuality of lifePediatricsWhite matterMedulloblastomaNeurocognitive

摘要: Recent advances in the delivery of cranial radiation therapy aim to reduce adverse neurocognitive outcomes associated with successful treatments. Damage white matter tracts following may result a reduction information processing speed, which turn lead declines academic achievement and performance scores on testing. This study reports language neurophysiological measures reflecting efficiency brain's capacity process semantic 14-year-old female treatment, included fractionated dosages, for medulloblastoma at age 10 years 3 months. The findings suggest skills par her peers stability general skill over 4 post-treatment.

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