Blastic NK-cell lymphomas (agranular CD4+CD56+ hematodermic neoplasms): a review.
作者： Tony Petrella , Martine Bagot , Rein Willemze , Marie Beylot-Barry , Béatrice Vergier
关键词: Biology 、 Lymphoma 、 Anatomical pathology 、 Pathology 、 Antigen 、 Neoplasm 、 Natural killer cell 、 Plasmacytoid dendritic cell 、 Cell 、 Blastic NK cell lymphoma
摘要: Blastic natural killer (NK) cell lymphoma (also termed CD4+CD56+ hematodermic neoplasm) is a recently described entity, with the first case reported in 1994. It was suggested initially that disease originates from NK cells. Since 1994, single cases and few small series have been published. In this review, data literature of 30 French Dutch study groups on cutaneous lymphomas are discussed. The major clinical, histopathologic, phenotypic aspects diagnostic criteria suggesting plasmacytoid dendritic origin for tumor cells provided.
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