Factors associated with early recurrence after congenital diaphragmatic hernia repair

作者: Luke R Putnam , Vikas Gupta , Kuojen Tsao , Carl F Davis , Pamela A Lally

DOI: 10.1016/J.JPEDSURG.2017.03.011

关键词: Extracorporeal membrane oxygenationLaparoscopySurgeryCongenital diaphragmatic herniaDiaphragmatic breathingThoracotomyThoracoscopyDiaphragmatic herniaLaparotomyMedicineAnesthesia

摘要: Abstract Background The purpose of this study was to identify patient and treatment characteristics associated with early (in hospital) hernia recurrence after congenital diaphragmatic (CDH) repair. Methods Data from the Congenital Diaphragmatic Hernia Study Group registry were queried 2007 2015. Recurrence initial repair prior death or discharge determined at time reoperation. Minimally invasive surgery (MIS) approaches included laparoscopy thoracoscopy, open consisted laparotomy thoracotomy. Multivariate regression analysis performed. Results Of 3984 patients, 3332 (84%) underwent CDH 76 (2.3%) patients had an recurrence. rate less variable over for undergoing vs thoracoscopy (range: 1.1–3.7% 1.7–8.9% annually). Timing repair, whether performed after, during, before ECMO did not significantly alter rates (0% 4.2% 3.0%, p =0.116). Larger defect size (C: OR 4.3, 95% CI 1.2–15.4; D: 7.1, 1.7–29.1) MIS approach (OR 3.2, 1.7–6.0) only independent predictors Conclusion higher recurrence, while use timing not. Type Treatment study. Level evidence II.

参考文章(15)
Gustavo Rocha, Inês Azevedo, Jorge Correia Pinto, Hercília Guimarães, Follow-up of the survivors of congenital diaphragmatic hernia Early Human Development. ,vol. 88, pp. 255- 258 ,(2012) , 10.1016/J.EARLHUMDEV.2011.08.025
Jacqueline Tsai, Jason Sulkowski, N. Scott Adzick, Holly L. Hedrick, Alan W. Flake, Patch repair for congenital diaphragmatic hernia: is it really a problem? Journal of Pediatric Surgery. ,vol. 47, pp. 637- 641 ,(2012) , 10.1016/J.JPEDSURG.2011.11.054
Kazuki Yokota, Hiroo Uchida, Kenichiro Kaneko, Yasuyuki Ono, Naruhiko Murase, Satoshi Makita, Masahiro Hayakawa, Surgical complications, especially gastroesophageal reflux disease, intestinal adhesion obstruction, and diaphragmatic hernia recurrence, are major sequelae in survivors of congenital diaphragmatic hernia. Pediatric Surgery International. ,vol. 30, pp. 895- 899 ,(2014) , 10.1007/S00383-014-3575-X
R.Lawrence Moss, Constance M. Chen, Michael R. Harrison, Prosthetic patch durability in congenital diaphragmatic hernia: A long-term follow-up study ☆ Journal of Pediatric Surgery. ,vol. 36, pp. 152- 154 ,(2001) , 10.1053/JPSU.2001.20037
Jason C. Fisher, Mary Jo Haley, Alejandro Ruiz-Elizalde, Charles J.H. Stolar, Marc S. Arkovitz, Multivariate model for predicting recurrence in congenital diaphragmatic hernia. Journal of Pediatric Surgery. ,vol. 44, pp. 1173- 1180 ,(2009) , 10.1016/J.JPEDSURG.2009.02.043
Pietro Bagolan, Francesco Morini, Long-term follow up of infants with congenital diaphragmatic hernia Seminars in Pediatric Surgery. ,vol. 16, pp. 134- 144 ,(2007) , 10.1053/J.SEMPEDSURG.2007.01.009
Tim Jancelewicz, Monping Chiang, Carol Oliveira, Priscilla P. Chiu, Late surgical outcomes among congenital diaphragmatic hernia (CDH) patients: Why long-term follow-up with surgeons is recommended Journal of Pediatric Surgery. ,vol. 48, pp. 935- 941 ,(2013) , 10.1016/J.JPEDSURG.2013.02.005
J.T. Wung, R. Sahni, S.T. Moffitt, E. Lipsitz, C.J.H. Stolar, Congenital diaphragmatic hernia: Survival treated with very delayed surgery, spontaneous respiration, and no chest tube☆☆☆ Journal of Pediatric Surgery. ,vol. 30, pp. 406- 409 ,(1995) , 10.1016/0022-3468(95)90042-X
KuoJen Tsao, Pamela A Lally, Kevin P Lally, Congenital Diaphragmatic Hernia Study Group, Minimally invasive repair of congenital diaphragmatic hernia Journal of Pediatric Surgery. ,vol. 46, pp. 1158- 1164 ,(2011) , 10.1016/J.JPEDSURG.2011.03.050