Safety issues and prospects for future generations of PPAR modulators

作者: A RUBENSTRUNK , R HANF , D HUM , J FRUCHART , B STAELS

DOI: 10.1016/J.BBALIP.2007.02.003

关键词: DyslipidemiaPeroxisome proliferator-activated receptorGlucose homeostasisPPAR agonistType 2 diabetesPharmacologySide effectMedicineAdverse effectInsulin resistance

摘要: … the nature of the side effect and the putative PPAR-related mechanism of action. This review … of PPAR agonists that could be of concern when considering the development of new PPAR …

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