MOF-derived Nanoporous Carbon as Intracellular Drug Delivery Carriers
作者： Nagy L. Torad , Yunqi Li , Shinsuke Ishihara , Katsuhiko Ariga , Yuichiro Kamachi
DOI: 10.1246/CL.131174
关键词: Micelle 、 Dendrimer 、 Nanoparticle 、 Intracellular drug delivery 、 Self-healing hydrogels 、 Carbonization 、 Chemistry 、 Biocompatibility 、 Nanotechnology 、 Drug carrier
摘要: Precursory Research for Embryon icSc ence and Technology (PRESTO), Japan Sc ogy Agency (JST),4-1-8 Honcho, Kawaguchi,Saitama 332-0012(E-mail: kevinwu@nims.go.jp, Yamauchi.Yusuke@nims.go.jp)We prepared nanoporous carbon (NC) particles of approx-imately 50-nm diameter by direct carbonization metalorganic frameworks (MOFs). The obtained MOF-derived NC(MOF-NC) exhibit very high biocompatibility and,hence, are promising as intracellular drug delivery carriers.Many carriers, such dendrimers, micelles, emul-sions, organicinorganic hybrids, nanoparticles, nanotubes, lip-osomes, (MOFs), hydrogels,have been proposed so far.
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