Serum from minimal change patients in relapse increases CD80 expression in cultured podocytes

作者: Takuji Ishimoto , Gabriel Cara-Fuentes , Heiman Wang , Michiko Shimada , Clive H. Wasserfall

DOI: 10.1007/S00467-013-2498-4

关键词: PrednisoneMedicineNephrologyExcretionMinimal change diseaseRenal functionReal-time polymerase chain reactionInternal medicineEndocrinologyNephrotic syndromeNephrosisPediatrics, Perinatology, and Child Health

摘要: Background Minimal change disease (MCD) is the most common cause of nephrotic syndrome in children and associated with expression CD80 podocytes increased excretion urine. We hypothesized that serum from patients MCD might stimulate cultured podocytes.

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