Potassium channel blocking agents

作者: Dorte Strøbæk , Lene Teuber , Bo Skaaning Jensen , Søren Peter Olesen , Dan Peters

DOI:

关键词: Polycystic kidney diseaseHyperinsulinemiaIrritable bowel syndromeIschemiaInternal medicineMigraineAnesthesiaCardiologyAnginaMedicineDementiaIntermittent claudication

摘要: This invention relates to novel potassium channel blocking agents, and their use in the preparation of pharmaceutical compositions. Moreover is directed compositions useful for treatment or alleviation diseases disorders associated with activity channels, particular asthma, cystic fibrosis, chronic obstructive pulmonary disease rhinorrhea, convulsions, vascular spasms, coronary artery renal disorders, polycystic kidney disease, bladder urinary incontinence, outflow obstruction, irritable bowel syndrome, gastrointestinal dysfunction, secretory diarrhoea, ischaemia, cerebral ischaemic heart angina pectoris, traumatic brain injury, psychosis, anxiety, depression, dementia, memory attention deficits, Alzheimer's dysmenorrhea, narcolepsy, Reynaud's intermittent claudication, Sjorgren's migraine, arrhythmia, hypertension, absence seizures, myotonic muscle dystrophia, xerostomi, diabetes type II, hyperinsulinemia, premature labour, baldness, cancer, immune suppression.

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