Effect of serum concentration on Candida biofilm formation on acrylic surfaces

摘要: The biofilm formation of the oral fungal pathogen Candida on denture acrylic strips coated with saliva, serum and, saliva-serum pellicle were examined in vitro using albicans (four isolates), glabrata (three isolates) and tropicalis isolates). degree activity varied depending upon both isolate pellicle. Significantly increased (particularly serum)-coated was observed three isolates C. another protein-coated acrylics, increasing concentration Similar trends one glabrata, although effects pellicles not significant. In contrast, all a single protein-free control significantly higher than that saliva-coated strips, increase pellicle-admixed depended concentration. Candidal surfaces is essentially promoted This suggests inflammation environment would facilitate colonization acrylic.