Ocular motor abnormalities in human immunodeficiency virus infection
作者： Pauline T. Merrill , Gary D. Paige , Richard A. Abrams , Robert G. Jacoby , David B. Clifford
关键词: Acquired immunodeficiency syndrome (AIDS) 、 Encephalopathy 、 Pathology 、 Saccade 、 Asymptomatic 、 Fixation (visual) 、 Medicine 、 Complication 、 Pediatrics 、 Dementia 、 Eye disease 、 Neurology 、 Clinical neurology
摘要: We studied ocular motor performance in 47 subjects with human immunodeficiency virus (HIV) infection and 25 normal control subjects. Saccade accuracy was the most sensitive measure, being significantly poorer for all four HIV-positive groups (asymptomatic, acquired syndrome [AIDS] without dementia, AIDS AIDS-related complex) than While saccade duration peak velocity were not different across groups, scatter of increased groups. latency affected. In both simple complex antisaccade tasks, asymptomatic, AIDS, dementia made fewer correct-way antisaccades did Latencies trials, trials. Fixation stability worse group Smooth pursuit gain decreased least demanding trial. One or more abnormalities present 15 (88%) asymptomatic subjects, 11 (69%) complex, 14 (100%) patients dementia.
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