Colicins and microcins: the next generation antimicrobials.

作者: Osnat Gillor , Benjamin C. Kirkup , Margaret A. Riley

DOI: 10.1016/S0065-2164(04)54005-4

关键词: Computational biologyHuman healthColicinBacteriocinAntimicrobialMicrobiologyBiology

摘要: Publisher Summary This chapter focuses on the bacteriocins produced by E. coli— namely, colicins and microcins explores their potential role in agriculture, bioaugmentation, human health. Colicins are primary defense systems found Escherichia coli . The antimicrobial properties of make them excellent candidates for application veterinary medicine. particularly that specifically kill animal pathogens, thereby illustrating these compounds to serve as next generation antibiotics. Microcins can also be useful indicators pathogen presence poultry. provides an overview novel uses new antibiotics generated form colcins microcins. Some toxins induce apoptosis some share common features with apoptosis-induced proteins. As a result they have becoming attractive tool understand might utilized cell targeted drugs. Finally, this abundant diverse family has real pharmaceuticals.

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