HER-2/ neu Gene Amplification in Esophageal Adenocarcinoma and Its Influence on Survival

作者: Sarah K. Thompson , Thomas R. Sullivan , Ruth Davies , Andrew R. Ruszkiewicz

DOI: 10.1245/S10434-011-1554-1

关键词: EsophagectomySurvival rateAdenocarcinomaMedicineCancerOncologyInternal medicineIncidence (epidemiology)Surgical oncologyProspective cohort studyGene duplication

摘要: Background HER-2/neu (c-erbB-2, HER2) gene amplification and protein overexpression have been associated with poor prognosis in several solid tumors, including breast gastric cancer. Its incidence significance esophageal adenocarcinoma is unknown.

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