Autocrine activation of PDGFRα promotes the progression of ovarian cancer
作者： D Matei , R E Emerson , Y-C Lai , L A Baldridge , J Rao
关键词: Endocrinology 、 Autocrine signalling 、 Carcinogenesis 、 Receptor 、 Internal medicine 、 MAPK/ERK pathway 、 Growth factor receptor 、 Platelet-derived growth factor receptor 、 Ovarian cancer 、 Biology 、 Cancer research 、 Platelet-derived growth factor
摘要: … (b) Effects of stimulation with peritoneal fluid in OVCA 2 primary cells. 1: Serum starved, 2: stimulated with peritoneal fluid, 3: peritoneal fluid preincubated with anti-PDGF AB antibody (…
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researchgate.net 参考文章(31)
A. Eriksson, A. Siegbahn, B. Westermark, C.H. Heldin, L. Claesson-Welsh, PDGF alpha- and beta-receptors activate unique and common signal transduction pathways. The EMBO Journal. ,vol. 11, pp. 543- 550 ,(1992) , 10.1002/J.1460-2075.1992.TB05085.X
William J. LaRochelle, Michael Jeffers, William F. McDonald, Rajeev A. Chillakuru, Neill A. Giese, Nathalie A. Lokker, Carol Sullivan, Ferenc L. Boldog, Meijia Yang, Corine Vernet, Catherine E. Burgess, Elma Fernandes, Lisa L. Deegler, Beth Rittman, Juliette Shimkets, Richard A. Shimkets, Jonathan M. Rothberg, Henri S. Lichenstein, PDGF-D, a new protease-activated growth factor Nature Cell Biology. ,vol. 3, pp. 517- 521 ,(2001) , 10.1038/35074593
Steven A. Rosenberg, Vincent T. DeVita, Samuel Hellman, Cancer : Principles and Practice of Oncology ,(1982)
Yanhua Hu, Güunther Böck, Georg Wick, Qingbo Xu, Activation of PDGF receptor α in vascular smooth muscle cells by mechanical stress The FASEB Journal. ,vol. 12, pp. 1135- 1142 ,(1998) , 10.1096/FASEBJ.12.12.1135
Alan N. Gordon, John T. Fleagle, David Guthrie, David E. Parkin, Martin E. Gore, Angel J. Lacave, Recurrent Epithelial Ovarian Carcinoma: A Randomized Phase III Study of Pegylated Liposomal Doxorubicin Versus Topotecan Journal of Clinical Oncology. ,vol. 19, pp. 3312- 3322 ,(2001) , 10.1200/JCO.2001.19.14.3312
Roy A. Jensen, John F. Beeler, Mohammad A. Heidaran, William J. LaRochelle, Characterization of baculovirus-expressed human alpha and beta platelet-derived growth factor receptors. Biochemistry. ,vol. 31, pp. 10887- 10892 ,(1992) , 10.1021/BI00159A032
Jeffrey P Zwerner, William A May, PDGF-C is an EWS/FLI induced transforming growth factor in Ewing family tumors. Oncogene. ,vol. 20, pp. 626- 633 ,(2001) , 10.1038/SJ.ONC.1204133
R Yao, G. Cooper, Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor Science. ,vol. 267, pp. 2003- 2006 ,(1995) , 10.1126/SCIENCE.7701324
H Lassus, H Sihto, A Leminen, S Nordling, H Joensuu, N N Nupponen, R Butzow, Genetic alterations and protein expression of KIT and PDGFRA in serous ovarian carcinoma British Journal of Cancer. ,vol. 91, pp. 2048- 2055 ,(2004) , 10.1038/SJ.BJC.6602252
Karin Aase, Alexandra Abramsson, Linda Karlsson, Christer Betsholtz, Ulf Eriksson, Expression analysis of PDGF-C in adult and developing mouse tissues. Mechanisms of Development. ,vol. 110, pp. 187- 191 ,(2002) , 10.1016/S0925-4773(01)00560-3