Oxidative Stress in Cardiovascular Disease: Potential Biomarkers and Their Measurements

摘要: The oxygen atmosphere surrounding us produces continuous oxidative stress because of the incomplete reduction O2 molecule. Oxidative mainly occurs in any system when generation reactive species (ROS) exceeds system’s ability to neutralize and eliminate them. This imbalance ROS can result from various pathways. Overproduction their limited removal mitochondrial respiratory chain, a lack antioxidant capacity, exposure environmental or behavioral stressors, etc. Such accumulation cause damage all biomolecules, including lipids, proteins, DNA. For this reason, has been implicated growing list human diseases such as cancer, atherosclerosis, Parkinson’s disease, heart failure, myocardial infarction, Alzheimer’s fragile X syndrome, etc., well aging process. Chronic disease is major death worldwide present era, it known that plays crucial role morbidity mortality due cardiovascular disease. It therefore very important measure check health. There are many techniques available it. include measurement lipid peroxidation products, volatile hydrocarbons breath, oxidized DNA bases urine. In review, we will discuss potential biomarkers methods measuring stress.