Microarray analysis of microRNA expression in cutaneous squamous cell carcinoma.
作者： Michael Sand , Marina Skrygan , Dimitrios Georgas , Daniel Sand , Stephan A. Hahn
DOI: 10.1016/J.JDERMSCI.2012.09.004
关键词: Messenger RNA 、 Gene 、 RNA 、 Gene silencing 、 microRNA 、 Molecular biology 、 Dicer 、 Microarray analysis techniques 、 Biology 、 Drosha
摘要: MicroRNAs (miRNAs) are a relatively new class of non-coding RNA molecules. They 17-21 nucleotides (nt) in length and capable post-transcriptional gene silencing [1]. Pri-miRNAs transcribed the nucleus by polymerases II III before being processed miRNA maturing enzymes, Drosha (intranuclear) Dicer (extranuclear). The latter enzyme is also part RNA-induced complex (RISC), which regulates function once mature has been loaded onto it. After Watson-Crick base pairing occurs between target mRNA 5’ “seed region” RISC-loaded miRNA, will either be translationally repressed (in case weak mRNA/miRNA complementarity) or cleaved strong causing posttranscriptional [2]. Despite significant potential for miRNA-based therapy, little research performed on roles cutaneous squamous cell carcinoma (cSCC).
core.ac.uk
springer.com
sci-hub.se 参考文章(52)
M. Sand, M. Skrygan, D. Sand, D. Georgas, S. A. Hahn, T. Gambichler, P. Altmeyer, F.G. Bechara, Expression of microRNAs in basal cell carcinoma. British Journal of Dermatology. ,vol. 167, pp. 847- 855 ,(2012) , 10.1111/J.1365-2133.2012.11022.X
John Quackenbush, Computational analysis of microarray data Nature Reviews Genetics. ,vol. 2, pp. 418- 427 ,(2001) , 10.1038/35076576
Regalla Kumarswamy, Giridhar Mudduluru, Paolo Ceppi, Santoshi Muppala, Miroslaw Kozlowski, Jacek Niklinski, Mauro Papotti, Heike Allgayer, MicroRNA-30a inhibits epithelial-to-mesenchymal transition by targeting Snai1 and is downregulated in non-small cell lung cancer International Journal of Cancer. ,vol. 130, pp. 2044- 2053 ,(2012) , 10.1002/IJC.26218
Jeong Hong Kim, Jung Hyun Chang, Joo-Heon Yoon, Jeung Gweon Lee, Jung Ho Bae, Kyung-Su Kim, 15-Lipoxygenase-1 induced by interleukin-4 mediates apoptosis in oral cavity cancer cells Oral Oncology. ,vol. 42, pp. 825- 830 ,(2006) , 10.1016/J.ORALONCOLOGY.2005.12.004
Piotr Dziunycz, Guergana Iotzova-Weiss, Jyrki J. Eloranta, Severin Läuchli, Jürg Hafner, Lars E. French, Günther F.L. Hofbauer, Squamous cell carcinoma of the skin shows a distinct microRNA profile modulated by UV radiation. Journal of Investigative Dermatology. ,vol. 130, pp. 2686- 2689 ,(2010) , 10.1038/JID.2010.169
Hironori Matsuyama, Hiroshi I. Suzuki, Hikaru Nishimori, Masaaki Noguchi, Takashi Yao, Norio Komatsu, Hiroyuki Mano, Koichi Sugimoto, Kohei Miyazono, miR-135b mediates NPM-ALK-driven oncogenicity and renders IL-17-producing immunophenotype to anaplastic large cell lymphoma. Blood. ,vol. 118, pp. 6881- 6892 ,(2011) , 10.1182/BLOOD-2011-05-354654
Man Lung Yeung, Jun-ichirou Yasunaga, Yamina Bennasser, Nelson Dusetti, David Harris, Nafees Ahmad, Masao Matsuoka, Kuan-Teh Jeang, Roles for MicroRNAs, miR-93 and miR-130b, and Tumor Protein 53–Induced Nuclear Protein 1 Tumor Suppressor in Cell Growth Dysregulation by Human T-Cell Lymphotrophic Virus 1 Cancer Research. ,vol. 68, pp. 8976- 8985 ,(2008) , 10.1158/0008-5472.CAN-08-0769
Joseph A. Jude, Mythili Dileepan, Subbaya Subramanian, Julian Solway, Reynold A. Panettieri, Timothy F. Walseth, Mathur S. Kannan, miR-140-3p regulation of TNF-α-induced CD38 expression in human airway smooth muscle cells American Journal of Physiology-lung Cellular and Molecular Physiology. ,vol. 303, ,(2012) , 10.1152/AJPLUNG.00041.2012
Masayuki Kano, Naohiko Seki, Naoko Kikkawa, Lisa Fujimura, Isamu Hoshino, Yasunori Akutsu, Takeshi Chiyomaru, Hideki Enokida, Masayuki Nakagawa, Hisahiro Matsubara, miR‐145, miR‐133a and miR‐133b: Tumor‐suppressive miRNAs target FSCN1 in esophageal squamous cell carcinoma International Journal of Cancer. ,vol. 127, pp. 2804- 2814 ,(2010) , 10.1002/IJC.25284
Tao Yu, Xiao-yi Wang, Ren-guo Gong, An Li, Sen Yang, Yu-tang Cao, Yu-ming Wen, Chang-mei Wang, Xin-zhu Yi, The expression profile of microRNAs in a model of 7,12-dimethyl-benz[a]anthrance-induced oral carcinogenesis in Syrian hamster. Journal of Experimental & Clinical Cancer Research. ,vol. 28, pp. 64- 64 ,(2009) , 10.1186/1756-9966-28-64