Case analysis of NOD-SCID mouse with patient-derived tumor xenogrraft models of gastric cancer

作者： Shu Xiang , Liu Xia , Dong Jing

DOI:

关键词: Lymphatic system 、 CD43 、 Lymphoma 、 Tumor M2-PK 、 Cancer 、 Immunohistochemistry 、 Transplantation 、 Pathology 、 Nod 、 Biology

摘要: Objective: The tumor type and the pathological features of were identified in murine xenografts model gastric cancer. Methods: histopathologic was observed by HE stainings; expression CD43, CD45RB, CD57, CK mouse CD43 CD57 spleen analyzed immunohistochemical method to diagnose types sources. Results: histological characteristics subcutaneous not consistent with human cancer observation. markers positive analysis, indicating that cells constituted T lymphocytes, B lymphocytes NK cells. But spleen, all negative. Conclusion: tumors NOD-SCID mice lymphoma derived from lymphoid tissue transplantation.

暂无可下载资源，当前可以选择系统获取到有开放资源时通知我或者直接发起求助文献求助

参考文章(10)

Dai Fukumura, Peigen Huang, Rakesh K Jain, Susan V Westmoreland, Spontaneous nonthymic tumors in SCID mice. Comparative Medicine. ,vol. 61, pp. 227- 234 ,(2011)

Giuseppe Navarra, Gian Luigi Adani, Elisabetta Bardella, Simona Ascanelli, Alessandro Turini, Enzo Pozza, Primary rectal lymphoma as a cause of bowel obstruction. Report of a case. Tumori. ,vol. 89, pp. 88- 90 ,(2003) , 10.1177/030089160308900119

G. C. Bosma, R. P. Custer, M. J. Bosma, Severe combined immunodeficiency (SCID) in the mouse. Pathology, reconstitution, neoplasms. American Journal of Pathology. ,vol. 120, pp. 464- 477 ,(1985)

M. Prochazka, H. R. Gaskins, L. D. Shultz, E. H. Leiter, The nonobese diabetic scid mouse: model for spontaneous thymomagenesis associated with immunodeficiency. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 89, pp. 3290- 3294 ,(1992) , 10.1073/PNAS.89.8.3290

S L Locatelli, A Giacomini, A Guidetti, L Cleris, R Mortarini, A Anichini, A M Gianni, C Carlo-Stella, Perifosine and sorafenib combination induces mitochondrial cell death and antitumor effects in NOD/SCID mice with Hodgkin lymphoma cell line xenografts. Leukemia. ,vol. 27, pp. 1677- 1687 ,(2013) , 10.1038/LEU.2013.28

Yuko Ito, Kohei Matsushita, Takuma Tsuchiya, Yukari Kohara, Tsuyoshi Yoshikawa, Makoto Sato, Keisuke Kitaura, Satoshi Matsumoto, Spontaneous nephroblastoma with lung metastasis in a rat. Journal of Toxicologic Pathology. ,vol. 27, pp. 91- 95 ,(2014) , 10.1293/TOX.2013-0059

Jeetendra Eswaraka, Anand Giddabasappa, Guangzhou Han, Kush Lalwani, Koleen Eisele, Zheng Feng, Timothy Affolter, James Christensen, Gang Li, Axitinib and crizotinib combination therapy inhibits bone loss in a mouse model of castration resistant prostate cancer BMC Cancer. ,vol. 14, pp. 742- 742 ,(2014) , 10.1186/1471-2407-14-742

Nobuhiro Kanaji, Akira Tadokoro, Kentaro Susaki, Saki Yokokura, Kiyomi Ohmichi, Reiji Haba, Naoki Watanabe, Shuji Bandoh, Tomoya Ishii, Hiroaki Dobashi, Takuya Matsunaga, Higher susceptibility of NOD/LtSz-scid Il2rg (-/-) NSG mice to xenotransplanted lung cancer cell lines. Cancer management and research. ,vol. 6, pp. 431- 436 ,(2014) , 10.2147/CMAR.S71185

SUSAN J. ZUNINO, DAVID H. STORMS, JOHN W. NEWMAN, THERESA L. PEDERSEN, CARL L. KEEN, JONATHAN M. DUCORE, Oral or parenteral administration of curcumin does not prevent the growth of high-risk t(4;11) acute lymphoblastic leukemia cells engrafted into a NOD/SCID mouse model. International Journal of Oncology. ,vol. 42, pp. 741- 748 ,(2013) , 10.3892/IJO.2012.1734

10.

Chie Kato, Etsuko Fujii, Yu Jau Chen, Berwini B Endaya, Koichi Matsubara, Masami Suzuki, Yasuyuki Ohnishi, Norikazu Tamaoki, Spontaneous thymic lymphomas in the non-obese diabetic/Shi-scid, IL-2Rγnull mouse: Laboratory Animals. ,vol. 43, pp. 402- 404 ,(2009) , 10.1258/LA.2009.009012

Case analysis of NOD-SCID mouse with patient-derived tumor xenogrraft models of gastric cancer

来源期刊

我的账户

Case analysis of NOD-SCID mouse with patient-derived tumor xenogrraft models of gastric cancer

来源期刊

相似文章 0

我的账户