Phosphorylated IκBα Predicts Poor Prognosis in Activated B-Cell Lymphoma and Its Inhibition with Thymoquinone Induces Apoptosis via ROS Release

作者: Azhar R. Hussain , Shahab Uddin , Maqbool Ahmed , Fouad Al-Dayel , Prashant P. Bavi

DOI: 10.1371/JOURNAL.PONE.0060540

关键词: LymphomaFlow cytometryThymoquinoneIκBαCancer researchCell cultureViability assayBiologyB-cell lymphomaApoptosisImmunologyGeneral Biochemistry, Genetics and Molecular BiologyGeneral Agricultural and Biological SciencesGeneral Medicine

摘要: … ROS release in ABC cells. Finally, to determine the mode of generation of ROS by TQ, we pre-treated ABC cell … for 24 hours and examined the cells for apoptosis by flow cytometry. As …

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