Sanjecumins A and B: new limonoids from Sandoricum koetjape

作者: Yuta Nagakura , Alfarius Eko Nugroho , Yusuke Hirasawa , Takahiro Hosoya , Abdul Rahman

DOI: 10.1007/S11418-012-0677-4

关键词: Cell cultureNitric oxideStereochemistrySandoricum koetjapeChemistryPharmacology toxicology

摘要: Two new limonoids, sanjecumins A (1) and B (2), have been isolated from the leaves of Sandoricum koetjape, together with sandoripins (3) (4). Their structures absolute configurations were elucidated on basis NMR CD data. Sandoripins (4) moderately inhibited nitric oxide production in mouse macrophage-like cell line J774.1 stimulated by lipopolysaccharide.

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